Genetically modified mosquitoes

Discrete-time models with mosquitoes carrying genetically-modified bacteria.

We formulate a homogeneous model and a stage-structured model for the interactive wild mosquitoes and mosquitoes carrying genetically-modified bacteria. We establish conditions for the existence and stability of fixed points for both models. We show that a unique positive fixed point exists and is asymptotically stable if the two boundary fixed points are both unstable. The unique positive fixe...

Control of vector populations using genetically modified mosquitoes.

The ineffectiveness of current strategies for chemical control of mosquito vectors raises the need for developing novel approaches. Thus, we carried out a literature review of strategies for genetic control of mosquito populations based on the sterile insect technique. One of these strategies consists of releasing radiation-sterilized males into the population; another, of integrating a dominan...

Biosafety concerns involving genetically modified mosquitoes to combat malaria and dengue in developing countries.

Awareness and Support of Release of Genetically Modified “Sterile” Mosquitoes, Key West, Florida, USA

After a dengue outbreak in Key West, Florida, during 2009-2010, authorities, considered conducting the first US release of male Aedes aegypti mosquitoes genetically modified to prevent reproduction. Despite outreach and media attention, only half of the community was aware of the proposal; half of those were supportive. Novel public health strategies require community engagement.

An introduction to ecological challenges concerning the use of genetically-modified mosquitoes for disease control

Vector-borne diseases such as malaria and dengue constitute a major obstacle to socio-economic development in much of the tropics and remain high on the list of priorities for the improvement of public health. Sadly, financial as well as logistical constraints prevent a rapid amelioration of this situation (Reducing risks, promoting healthy life 2002). Unlike other infectious diseases, vector-b...